Vancouver has a large anime and manga related convention called Anime Evolution that I've attended as a convention goer and an artist ever since its inception at SFU. It is a grand place to see the talented artists we have in Vancouver in the Artist's Alley and of course to gorge on fine, imported Japanese popular culture.
Two of my favorite artists Nina Matsumoto and Camilla d’Errico whose careers I've had the pleasure of seeing explode into book deals and online and offline fame will be attending the convention this year.
Ayden Gallery in Tinseltown has combined manga style art with surrealism.
Other conventions going on in Vancouver this year:
Aug 13-1 5
Vancouver Comic Con
Aug 29 (happens once per month)
Vancouver's Convention of Science Fiction and Fantasy
Surrey International Writer's Conference